Aeroallergen sensitization rates in military children with rhinitis symptoms

Christopher W Calabria1, John Dice

  • 1Department of Allergy and Immunology, Wilford Hall Medical Center, Lackland AFB, Texas 78236, USA. christopher.calabria@lackland.af.mil

Insights

Childhood aeroallergen sensitization is common and increases with age. Perennial allergens are most prevalent in young children, with rates for many allergens underreported in previous studies.

Area of Science:

  • Pediatric Allergy and Immunology
  • Environmental Health
  • Immunology

Background:

  • Childhood sensitization rates to common aeroallergens are frequently underestimated.
  • Rhinitis is a common condition in children, often linked to environmental allergens.

Purpose of the Study:

  • To determine aeroallergen sensitization prevalence in military children with rhinitis.
  • To analyze the age-related development of atopy to perennial and seasonal allergens.

Main Methods:

  • Retrospective analysis of a skin testing database for children aged 18 and younger.
  • Skin prick testing performed using either an 8-test screening panel or a comprehensive 51-allergen panel.

Main Results:

  • 35.4% of children tested with the 8-test panel had positive results; atopy increased significantly with age.
  • With the 51-allergen panel, 80.3% of children showed at least one positive result, averaging 11.4 positive tests.
  • Common allergens included mold, cat, dust mite, grasses, and trees; perennial allergens predominated in younger children.

Conclusions:

  • Aeroallergen sensitization is highly prevalent in children and escalates with age.
  • Perennial allergens are the primary sensitizers in children under three years old.
  • The study provides data on underreported allergens, applicable beyond a military population.
Abstract

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