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Updated: Jul 12, 2026

Intracameral Injection in Rats with Low Risk of Adverse Effects
Published on: May 31, 2024
[Toxicity of intravitreal injections of antibiotics and antivirals]
1Service d'Ophtalmologie, Hôpital St Pierre, Universitè Libre de Bruxelles, Bruxelles. info@stpierre-bru.be
Abstract:
Intravitreal injections of antivirals, antifungals and antibiotics are very efficacious in the management of intraocular infections, which is not the case with per os, intravenous or peribulbar administration. However, these drugs have some toxic potential, more pronounced if used in intraocular condition. Being too toxic, aminoglycosides have been replaced by Ceftazidime and Vancomycine in the management of bacterial endophthalmitis. Efficacy of these drugs for prophylactic use is not demonstrated and their toxic potential remains to be kept in mind.
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