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A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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Zinc lowers amyloid-beta toxicity by selectively precipitating aggregation intermediates

K Garai1, B Sahoo, S K Kaushalya

  • 1Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India.

Biochemistry
|August 28, 2007
PubMed
Summary

Zinc ions (Zn2+) destabilize soluble amyloid-beta (Abeta) aggregates, which are implicated in Alzheimer's disease. This action reduces Abeta

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