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Profiles of some clinical chemical parameters in growing dwarf and landrace kids
1Department of Clinical Studies, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Insights
Age significantly impacts clinical chemistry reference values in young goats. Factors like breed and herd also play a role, with sex having minimal influence on these key health indicators.
Area of Science:
- Veterinary Medicine
- Animal Science
- Biochemistry
Background:
- Establishing reference ranges for clinical chemistry parameters is crucial for assessing animal health.
- Age-related physiological changes can significantly alter biochemical profiles in young animals.
- Understanding breed and herd-specific variations is important for accurate health monitoring in goats.
Purpose of the Study:
- To determine reference ranges and age-specific profiles for various plasma biochemical parameters in young goats.
- To investigate the influence of age, breed, herd, and sex on these clinical chemical values.
- To provide a foundation for accurate health assessments in growing goats.
Main Methods:
- Analysis of plasma creatinine, urea, bilirubin, glucose, cholesterol, calcium, magnesium, sodium, potassium, inorganic phosphorus, and total serum proteins.
- Study conducted on Dwarf and Danish Landrace goat kids from birth to 12 months.
- Comparison of parametric and nonparametric statistical values to establish reference ranges.
Main Results:
- Plasma levels of creatinine, urea, and total serum proteins increased with age.
- Glucose and cholesterol levels were highest at birth and decreased over time.
- Electrolyte concentrations remained stable; significant variations noted across age, breed, and herd.
Conclusions:
- Age is the primary determinant of clinical chemical reference values in young goats.
- Herd and breed significantly influence these values, while sex has a negligible effect on most parameters.
- These findings are essential for interpreting biochemical data and diagnosing health issues in young goats.
Abstract:
Plasma creatinine, urea, bilirubin, glucose, cholesterol, calcium, magnesium, sodium, potassium, inorganic phosphorus and total serum proteins were analyzed in kids of Dwarf and Danish Landrace breeds from birth to 12 months of age. The purpose was to determine the reference ranges, age profiles and the influence of other factors. Comparisons between parametric (mean +/- standard deviation) and the corresponding nonparametric (5th and 95th percentile, median) values were calculated for each parameter, the results of which indicated no apparent differences. The levels were very much dependent on age. Creatinine, urea and total serum protein levels increased gradually with age. Glucose and cholesterol levels were high at birth and then decreased with age. The electrolyte concentrations were maintained within narrow limits. Significant differences were observed between kids of different ages (within the breeds), breeds (within similar age) and herds (within the same age and breed). Differences between female and male Landrace kids of the same ages were observed in plasma urea, creatinine, glucose and total serum proteins. It is concluded that age has a major influence on the clinical chemical reference values in young goats, followed by herd and breed, but the influence of sex was small and is negligible in most parameters.