Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 12, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

An exposimetry system using tissue-mimicking liquid.

Timothy A Stiles1, Ernest L Madsen, Gary R Frank

  • 1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706, USA. tastiles@wisc.edu

Ultrasound in Medicine & Biology
|August 28, 2007
PubMed
Summary

Current diagnostic ultrasound measurements may underestimate acoustic pressure and intensity. This study introduces a new tissue-mimicking liquid and method to provide more accurate in situ measurements, improving diagnostic ultrasound safety and efficacy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phantoms for Quantitative Ultrasound.

Advances in experimental medicine and biology·2023
Same author

Pulse-Echo Quantitative US Biomarkers for Liver Steatosis: Toward Technical Standardization.

Radiology·2022
Same author

Corrigendum to 'LOW-ECHO SPHERE PHANTOMS AND METHODS FOR ASSESSING IMAGING PERFORMANCE OF MEDICAL ULTRASOUND SCANNERS' [ULTRASOUND MED BIOL 40 (2014) 1697-1717].

Ultrasound in medicine & biology·2019
Same author

Low-echo sphere phantoms and methods for assessing imaging performance of medical ultrasound scanners.

Ultrasound in medicine & biology·2014
Same author

Evaluation of the impact of backscatter intensity variations on ultrasound attenuation estimation.

Medical physics·2013
Same author

Comparison of ultrasound attenuation and backscatter estimates in layered tissue-mimicking phantoms among three clinical scanners.

Ultrasonic imaging·2012

Area of Science:

  • Medical Physics
  • Biomedical Engineering
  • Diagnostic Ultrasound

Background:

  • Current acoustic output measurements for diagnostic ultrasound scanners use water and a derating scheme.
  • This derating method neglects nonlinear sound wave propagation, potentially underestimating pressure and intensity in tissue-mimicking media.
  • Previous studies indicate that derating inaccuracies can lead to significant underestimations of relevant acoustic parameters.

Purpose of the Study:

  • To describe an alternative method for acoustic output measurements using a novel tissue-mimicking liquid.
  • To evaluate the accuracy of this new method compared to traditional derating schemes.
  • To assess the stability and acoustic properties of the developed tissue-mimicking liquid.

Main Methods:

More Related Videos

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Related Experiment Videos

Last Updated: Jul 12, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

  • Development of a tissue-mimicking liquid with specific acoustic properties: attenuation coefficient slope of 0.3 dB/cm/MHz, speed of sound of 1,540 m/s, and nonlinearity parameter B/A of 7.5.
  • Characterization of the liquid's acoustic property stability over time (at least 2 years).
  • Initial acoustic output measurements using a single M-mode configuration with the new liquid.

    • Main Results:

    • The developed tissue-mimicking liquid exhibits stable acoustic properties.
    • Initial M-mode measurements demonstrate that the traditional derating method significantly underestimates the pulse intensity integral.
    • The peak rarefactional pressure is also shown to be underestimated by the current derating scheme.

    Conclusions:

    • The proposed alternative method using a specialized tissue-mimicking liquid offers a more accurate approach to acoustic output measurements.
    • Traditional derating methods in diagnostic ultrasound can lead to substantial underestimation of key acoustic parameters.
    • This improved measurement technique has implications for ensuring the safety and efficacy of diagnostic ultrasound procedures.