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An exposimetry system using tissue-mimicking liquid.

Timothy A Stiles1, Ernest L Madsen, Gary R Frank

  • 1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706, USA. tastiles@wisc.edu

Ultrasound in Medicine & Biology
|August 28, 2007
PubMed
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Current diagnostic ultrasound measurements may underestimate acoustic pressure and intensity. This study introduces a new tissue-mimicking liquid and method to provide more accurate in situ measurements, improving diagnostic ultrasound safety and efficacy.

Area of Science:

  • Medical Physics
  • Biomedical Engineering
  • Diagnostic Ultrasound

Background:

  • Current acoustic output measurements for diagnostic ultrasound scanners use water and a derating scheme.
  • This derating method neglects nonlinear sound wave propagation, potentially underestimating pressure and intensity in tissue-mimicking media.
  • Previous studies indicate that derating inaccuracies can lead to significant underestimations of relevant acoustic parameters.

Purpose of the Study:

  • To describe an alternative method for acoustic output measurements using a novel tissue-mimicking liquid.
  • To evaluate the accuracy of this new method compared to traditional derating schemes.
  • To assess the stability and acoustic properties of the developed tissue-mimicking liquid.

Main Methods:

Related Experiment Videos

  • Development of a tissue-mimicking liquid with specific acoustic properties: attenuation coefficient slope of 0.3 dB/cm/MHz, speed of sound of 1,540 m/s, and nonlinearity parameter B/A of 7.5.
  • Characterization of the liquid's acoustic property stability over time (at least 2 years).
  • Initial acoustic output measurements using a single M-mode configuration with the new liquid.

    • Main Results:

    • The developed tissue-mimicking liquid exhibits stable acoustic properties.
    • Initial M-mode measurements demonstrate that the traditional derating method significantly underestimates the pulse intensity integral.
    • The peak rarefactional pressure is also shown to be underestimated by the current derating scheme.

    Conclusions:

    • The proposed alternative method using a specialized tissue-mimicking liquid offers a more accurate approach to acoustic output measurements.
    • Traditional derating methods in diagnostic ultrasound can lead to substantial underestimation of key acoustic parameters.
    • This improved measurement technique has implications for ensuring the safety and efficacy of diagnostic ultrasound procedures.