Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dentin in severe fluorosis: a quantitative histochemical study.

F Rojas-Sánchez1, M Alaminos, A Campos

  • 1Instituto de Investigaciones Odontológicas Raúl Vincentelli, Facultad de Odontología, Universidad Central de Venezuela, Caracas, Venezuela.

Journal of Dental Research
|August 28, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-time dosimetry, organs dose and risk assessment for CBCT thorax protocols in IGRT procedures.

Radiography (London, England : 1995)·2025
Same author

Search for a Hidden Sector Scalar from Kaon Decay in the Dimuon Final State at ICARUS.

Physical review letters·2025
Same author

Inclusion of ΑVβ3 integrin into extracellular vesicles in a caveolin-1 tyrosine-14- phosphorylation dependent manner and subsequent transfer to recipient melanoma cells promotes migration, invasion and metastasis.

Cell communication and signaling : CCS·2025
Same author

Magnetic functionalization of ZnO nanoparticles surfaces via optically generated methyl radicals.

The Journal of chemical physics·2023
Same author

Nanostructured fibrin-based hydrogel membranes for use as an augmentation strategy in Achilles tendon surgical repair in rats.

European cells & materials·2022
Same author

Subacute thyroiditis might be a complication triggered by SARS-CoV-2.

Endocrinologia, diabetes y nutricion·2021

Severe dental fluorosis causes dentin hypermineralization, a response to enamel damage. This finding suggests dentin

Area of Science:

  • Dental Science
  • Biomineralization
  • Fluoride Toxicology

Background:

  • Dentin exhibits hypermineralization in response to enamel alterations.
  • Dentin serves as a biomarker for fluoride exposure.
  • Severe enamel fluorosis may induce dentin hypermineralization.

Purpose of the Study:

  • To investigate dentin hypermineralization in severe dental fluorosis.
  • To compare mineral content in healthy and fluorotic teeth.
  • To understand dentin's response to enamel damage.

Main Methods:

  • Scanning electron microscopy (SEM) for structural analysis.
  • Quantitative electron-probe microanalysis (EPMA) for elemental composition.
  • Comparative analysis of dentin and enamel from healthy and fluorotic teeth.

Related Experiment Videos

Main Results:

  • Fluorotic dentin displayed a significantly more mineralized sclerotic pattern than control dentin (p < 0.001).
  • Enamel adjacent to fluorotic lesions showed hypercalcification compared to dentin (p < 0.001).
  • Dentin exhibited hypermineralization in response to severe enamel fluorosis.

Conclusions:

  • Severe dental fluorosis induces dentin hypermineralization, mirroring responses in other enamel disorders.
  • The dentin's hypermineralization mechanism warrants consideration in dental caries and fluorosis-related conditions.
  • This study highlights dentin's adaptive response to enamel damage from fluoride exposure.