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Updated: Jul 12, 2026
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Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Heterotopic ossification in patients after total hip replacement
Tomasz Stołtny1, Bogdan Koczy, Wojciech Wawrzynek
1Wojewódzki Szpital Chirurgii Urazowej im. dra J. Daaba, Piekary Slaskie. quattro42@poczta.onet.pl
Ortopedia, Traumatologia, Rehabilitacja
|August 28, 2007
Summary
Heterotopic ossification (HO) is abnormal bone growth in soft tissues, often complicating hip replacement. Prevention involves NSAIDs or radiotherapy, while treatment includes ESWT, surgery, and embolization.
Area of Science:
- Orthopedic Surgery
- Bone Biology
- Medical Complications
Background:
- Heterotopic ossification (HO) is pathological bone formation in soft tissues.
- It is a frequent complication following total hip arthroplasty, affecting nearly 90% of patients.
- Various risk factors contribute to HO development.
Purpose of the Study:
- To review the current literature on the prevention and treatment of heterotopic ossification.
- To provide an overview of the state-of-the-art strategies for managing HO.
Main Methods:
- Literature review of existing studies on HO prevention and treatment.
- Analysis of pharmacotherapy (NSAIDs), radiotherapy, extracorporeal shock wave therapy (ESWT), and surgical interventions.
- Discussion of pre-operative embolization techniques.
Main Results:
- NSAIDs and radiotherapy are primary prevention methods for HO.
- Symptomatic HO is managed with ESWT, surgery, and subsequent pharmacotherapy or radiotherapy.
- Arterial embolization is a common pre-surgical step.
Conclusions:
- Effective prevention and treatment strategies for HO are crucial in orthopedic surgery.
- A combination of approaches may be necessary for optimal patient outcomes.
- Further research may refine current management protocols.
