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Published on: June 13, 2018
Ulcerous lesions disclosing cutaneous infection with Fusarium solani
Lidia Pérez-Pérez1, Manuel Pereiro, Dolores Sánchez-Aguilar
1Department of Dermatology, Complejo Hospitalario Universitario, Santiago de Compostela, Spain. mejaime@usc.es
Abstract:
Fusarium spp. are emergent opportunistic moulds capable of producing life-threatening diseases, usually in immunocompromised hosts. When they infect immunocompetent patients, they usually cause localized diseases. We describe here a case of cutaneous fusariosis in a patient with a medical history of diabetes mellitus and non-Hodgkin's lymphoma who presented with two painful lesions on her left leg. The diagnosis was made on the basis of histopathological findings and skin biopsy culture. The lesions resolved after treatment with oral itraconazole. Cutaneous fusariosis manifests clinically as lesions that can be grouped into a few clinical patterns, and should always be considered in the differential diagnosis of necrotic cutaneous lesions.
Insights
Fusarium spp. infections, known as fusariosis, can cause serious disease, particularly in immunocompromised individuals. This case highlights cutaneous fusariosis in a diabetic patient, successfully treated with itraconazole.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Fusarium species are opportunistic molds causing infections, primarily in immunocompromised individuals.
- In immunocompetent hosts, Fusarium infections typically manifest as localized disease.
Observation:
- A patient with diabetes mellitus and non-Hodgkin's lymphoma presented with painful lesions on the left leg.
- Diagnosis of cutaneous fusariosis was confirmed through histopathological examination and skin biopsy culture.
Findings:
- The patient's cutaneous lesions resolved following treatment with oral itraconazole.
- Cutaneous fusariosis presents with various clinical patterns and should be considered in cases of necrotic skin lesions.
Implications:
- This case underscores the importance of considering cutaneous fusariosis in the differential diagnosis of necrotic skin lesions, even in non-immunocompromised patients.
- Antifungal treatment, such as itraconazole, can be effective in managing cutaneous fusariosis.
- Further research into the clinical spectrum and management of Fusarium infections is warranted.
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