Related Experiment Video
Updated: Jul 12, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Anxiety predicts mortality and morbidity after coronary artery and valve surgery--a 4-year follow-up study
Andrea Székely1, Piroska Balog, Erzsébet Benkö
1Department of Anesthesia and Intensive Care, Gottsegen György Hungarian Institute of Cardiology, Budapest, Hungary. szekelya@kardio.hu
Insights
High preoperative anxiety significantly increases mortality risk in cardiac surgery patients. Ongoing anxiety assessment can help identify those at risk for poor outcomes and cardiovascular events post-surgery.
Area of Science:
- Cardiology
- Psychosomatic Medicine
- Clinical Outcomes Research
Background:
- Psychosocial factors, particularly anxiety and depression, are increasingly recognized as significant determinants of health outcomes.
- Previous research on psychosocial factors and cardiac events has primarily focused on population studies or post-myocardial infarction cohorts, leaving a gap in understanding their impact after cardiac surgery.
Purpose of the Study:
- To investigate the long-term effects of anxiety and depression on patient outcomes following cardiac surgery.
- To determine if psychological factors can serve as predictors for mortality and cardiovascular events after major cardiac procedures.
Main Methods:
- A prospective study of 180 patients undergoing cardiac surgery with cardiopulmonary bypass, followed for 4 years.
- Assessment of anxiety (Spielberger State-Trait Anxiety Inventory, STAI-S/STAI-T) and depression (Beck Depression Inventory, BDI) preoperatively and at multiple time points post-discharge.
- Clinical endpoints included all-cause mortality and hospitalizations for cardiac events.
Main Results:
- Elevated preoperative trait anxiety scores (STAI-T >45) were significantly associated with increased mortality (p = .008).
- Independent predictors of mortality included postoperative congestive heart failure and preoperative trait anxiety.
- Cardiovascular hospitalizations were independently linked to longer intensive care unit stays and elevated anxiety levels at 6 months post-discharge.
Conclusions:
- Preoperative and ongoing anxiety assessment are valuable tools for risk stratification in cardiac surgery patients.
- Identifying patients with high anxiety levels can aid in the early detection of those at higher risk for mortality and cardiovascular morbidity.
- Integrating psychosocial assessments into routine care may improve patient management and outcomes after cardiac surgery.
Objective:
To explore the long-term effect of anxiety and depression on outcome after cardiac surgery. To date, the relationship between psychosocial factors and future cardiac events has been investigated mainly in population-based studies, in patients after cardiac catheterization or myocardial infarction.
Methods:
In total, 180 patients who underwent cardiac surgery using cardiopulmonary bypass were prospectively studied and followed up for 4 years. Anxiety (Spielberger State-Trait Anxiety Inventory, STAI-S/STAI-T), depression (Beck Depression Inventory, BDI), living alone, and education level along with clinical risk factors and perioperative characteristics were assessed. Psychological self-report questionnaires were completed preoperatively and 6, 12, 24, 36, and 48 months after discharge. Clinical end-points were mortality and cardiac events requiring hospitalization during follow-up.
Results:
Average preoperative STAI-T score was 44.6 +/- 10. Kaplan-Meier analysis showed a significant effect of preoperative STAI-T >45 points (p = .008) on mortality. In multivariate models, postoperative congestive heart failure (OR: 10.8; 95% confidence interval [CI]: 2.9-40.1; p = .009) and preoperative STAI-T (score OR: 1.07; 95% CI: 1.01-1.15; p = .05) were independently associated with mortality. The occurrence of cardiovascular hospitalization was independently associated with postoperative intensive care unit days (OR: 1.41; 95% CI: 1.01-1.96; p = .045) and post discharge 6th month STAI-T (OR: 1.06; 95% CI:1.01-1.13; p = .03).
Conclusions:
The results of the present study suggest that the assessment of psychosocial factors, particularly the ongoing assessment of anxiety, could help in risk stratification and identification of patients at risk of mortality and cardiovascular morbidity after cardiac surgery.
Related Concept Videos
Aneurysm IV: Nursing Management
Coronary Artery Disease IV: Preventive Measures
Aortic Regurgitation III: Medical Management
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Mitral Stenosis IV: Nursing Management