Nodular-type muscle sarcoidosis developing after a dog bite

Area of Science:

• Immunology
• Dermatology
• Neurology

Background:

• Sarcoidosis is a multisystem inflammatory disease of unknown etiology.
• Muscle involvement in sarcoidosis is uncommon, with nodular-type muscle sarcoidosis being particularly rare.

Observation:

• A 46-year-old woman presented with right thigh swelling secondary to a dog bite wound.
• Clinical examination, laboratory tests, imaging, and muscle biopsy were performed.

Findings:

• The diagnostic workup confirmed nodular-type muscle sarcoidosis.
• The findings indicate an unusual presentation of sarcoidosis.

Implications:

• This case highlights the potential for physical trauma, such as a dog bite, to trigger sarcoidosis.
• Genetic predisposition may play a role in the development of sarcoidosis following injury.