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Updated: Jul 12, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Nodular-type muscle sarcoidosis developing after a dog bite.

Y Koide¹, H Ishihara, F Kanda

¹Department of Neurology, Kasai City Hospital, 1-13 Yokoo, Hojo-cho, Kasai-shi, Hyogo 675-2393, Japan. yuri_jap@yahoo.com.jp

|August 29, 2007

Summary

A dog bite triggered a rare form of sarcoidosis in a 46-year-old woman, causing thigh swelling. This case suggests trauma may activate sarcoidosis in susceptible individuals.

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Last Updated: Jul 12, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Area of Science:

Immunology
Dermatology
Neurology

Background:

Sarcoidosis is a multisystem inflammatory disease of unknown etiology.
Muscle involvement in sarcoidosis is uncommon, with nodular-type muscle sarcoidosis being particularly rare.

Observation:

A 46-year-old woman presented with right thigh swelling secondary to a dog bite wound.
Clinical examination, laboratory tests, imaging, and muscle biopsy were performed.

Findings:

The diagnostic workup confirmed nodular-type muscle sarcoidosis.
The findings indicate an unusual presentation of sarcoidosis.

Implications:

This case highlights the potential for physical trauma, such as a dog bite, to trigger sarcoidosis.
Genetic predisposition may play a role in the development of sarcoidosis following injury.