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Updated: Jul 12, 2026
06:59
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
[Acute intoxication with clonidine--a case report]
Adam Hajduk1, Jacek Sein Anand, Zygmunt Chodorowski
1Katedra i Klinika Chorób Wewnetrznych, Geriatrii i Toksykologii Klinicznej, Akademii Medycznej w Gdańsku.
Przeglad Lekarski
|August 30, 2007
Summary
A young woman survived a severe clonidine overdose (3,375 mg) after a suicide attempt. Prompt medical treatment, including gastric lavage and fluids, led to rapid symptom resolution and recovery.
Area of Science:
- Pharmacology
- Toxicology
- Emergency Medicine
Background:
- Clonidine, an alpha-2 adrenergic agonist, is used to treat hypertension and other conditions.
- Overdose of clonidine can lead to significant central nervous system and cardiovascular effects.
Observation:
- A 24-year-old female presented after ingesting 3,375 mg of clonidine in a suicide attempt.
- Initial symptoms included drowsiness, weakness, and hypotension (90/50 mmHg).
Findings:
- The patient was conscious but somnolent upon admission.
- Treatment involved gastric lavage and intravenous crystalloid infusion.
Implications:
- This case highlights the potential for severe toxicity with massive clonidine overdose.
- Rapid and appropriate medical intervention can lead to favorable outcomes even in significant ingestions.
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