[Therapeutic progress in gynecology: functional approaches]

Area of Science:

• Reproductive endocrinology and pharmacology.
• Evidence-based medicine and technological innovation.

Context:

• Hormone therapy management has evolved significantly over the past decade.
• Innovations include lower-dose estrogen and novel progestins in oral contraceptives.
• Optimized benefit/risk profiles for menopause hormone therapy through new formulations and administration routes.

Purpose:

• To review recent advancements in hormone therapy for contraception and menopause management.
• To highlight improvements in in vitro fertilization (IVF) techniques and outcomes.

Summary:

• Lower dosages and new progestins enhance oral contraceptive tolerance and non-contraceptive benefits.
• Optimized benefit/risk balance in menopause treatment via lower doses, new progestins, and novel administration routes.
• Approximately 500,000 IVF cycles annually improve fertility, reduce multiple pregnancies, and utilize new drugs like recombinant gonadotropins and LHRH antagonists, alongside cryopreservation techniques.

Impact:

• Improved patient tolerance and non-contraceptive benefits of oral contraceptives.
• Enhanced safety and efficacy of hormone therapy for menopausal symptoms.
• Increased success rates and reduced complications in assisted reproductive technologies like IVF.