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Published on: February 28, 2012
Evaluating patients with acute ischemic stroke with special reference to newly developed atrial fibrillation in
Minoru Tagawa1, Shigekazu Takeuchi, Masaomi Chinushi
1Department of Cardiology, Nagaoka Chuo General Hospital, Niigata 940-8653, Japan. m-tagawa@dc5.so-net.ne.jp
Insights
Holter ECG is crucial for detecting atrial fibrillation (AF) and paroxysmal atrial fibrillation (PAF) in cardioembolic stroke patients. This helps identify cardiovascular risk factors for better stroke management.
Area of Science:
- Cardiology
- Neurology
- Medical Diagnostics
Background:
- Cardioembolic strokes are severe and linked to poor outcomes.
- Identifying cardiovascular risk factors is essential for managing these strokes.
- Atrial fibrillation (AF) and paroxysmal atrial fibrillation (PAF) are key concerns.
Purpose of the Study:
- To evaluate cardiovascular status in acute ischemic stroke patients.
- To specifically assess the role of persistent AF and PAF.
- To correlate these findings with stroke type, particularly cardioembolic stroke.
Main Methods:
- 315 acute ischemic stroke patients were classified into cardioembolic, lacunar, atherothrombotic, and unclassified groups.
- Standard ECG, 24-hour Holter ECG, and transthoracic echocardiography (UCG) were performed on all patients.
- Brain imaging and clinical data were used for stroke classification.
Main Results:
- Persistent AF or PAF was detected in 31.5% of patients via Holter ECG, significantly more in the cardioembolic group (67.6%).
- Standard ECG identified new-onset AF/PAF in 5.2% of patients, with 13.3% in the cardioembolic group.
- Echocardiography revealed higher rates of left atrial enlargement and mitral regurgitation in cardioembolic stroke patients.
Conclusions:
- Holter ECG significantly improves the detection of AF and PAF compared to standard ECG alone.
- Early detection of AF/PAF is vital for managing patients with cardioembolic stroke.
- Integrating ECG and echocardiography aids in identifying cardiovascular risks associated with ischemic stroke.
Background:
Cardioembolic strokes are extensive and have a poor prognosis. To identify the cardiovascular risk factors of cardioembolic stroke, we evaluated the cardiovascular status with special reference to persistent atrial fibrillation (AF) and paroxysmal atrial fibrillation (PAF) combined with the type of acute ischemic stroke.
Methods:
We divided 315 consecutive patients admitted to our Department of Neurosurgery with an acute ischemic stroke into four types of brain infarction using clinical history, onset pattern of stroke, and brain imaging: cardioembolic (group E, n = 105), lacunar (group L, n = 92), atherothrombotic (group T, n = 111), and unclassified (n = 7). All patients underwent standard electrocardiography (ECG), a 24-hour ECG recording (Holter ECG) and transthoracic echocardiography (UCG).
Results:
Persistent AF or PAF was detected in 97 patients (31.5%) using Holter ECG: more frequently in group E (67.6%) than in groups L (15.2%) or T (9.2%). Persistent AF or PAF was first diagnosed on admission using a standard ECG in 16 patients (5.2%) with no previous history and 14 of these patients belonged to group E (13.3%). PAF was newly detected on Holter ECG in another 26 patients (8.4%) and 13 of these patients (12.4%) belonged to group E. Concerning UCG, left atrial enlargement and mitral regurgitation were more frequent in group E than in group L or T.
Conclusion:
Holter ECG in addition to ECG on admission is important for detecting persistent AF or PAF in patients with ischemic stroke, especially with cardioembolism as diagnosed by neuroimaging.
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