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A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Evaluation of root coverage with two connective tissue grafts obtained from the same location
Randall J Harris1, Laura E Harris, Christpoher R Harris
1University of Nebraska, Lincoln, Nebraska, USA.
Summary
This study found that a second connective tissue graft (CTG) provided greater root coverage than the first CTG. Both CTGs significantly improved periodontal measurements, with no significant differences between them except for the final root coverage percentage.
Area of Science:
- Periodontology
- Regenerative Dentistry
- Oral Surgery
Background:
- Connective tissue grafts (CTGs) are widely used for root coverage in periodontal plastic surgery.
- Assessing the impact of sequential graft harvesting from the same donor site on clinical outcomes is crucial for optimizing treatment.
- Understanding factors influencing graft success can improve patient care and surgical predictability.
Purpose of the Study:
- To compare the clinical root coverage achieved using two CTGs harvested sequentially from the same donor area.
- To evaluate the efficacy of subepithelial CTG placement for treating gingival recession.
- To determine if patient-specific factors or surgical timing influence root coverage outcomes.
Main Methods:
- Sixty patients with paired connective tissue grafts (first and second harvests from the same donor site) were included.
- Subepithelial grafts were utilized for root coverage procedures.
- Clinical parameters including recession, probing depth, keratinized tissue width, and attachment level were measured before and after surgery.
Main Results:
- Both first and second CTGs resulted in statistically significant improvements in all measured clinical parameters.
- No statistically significant differences were observed in clinical changes between the first and second CTGs, except for the mean root coverage percentage.
- The second CTG achieved a statistically significant higher mean root coverage (98.2%) compared to the first CTG (95.4%).
Conclusions:
- Sequential harvesting of connective tissue grafts from the same donor site is effective for root coverage.
- The second connective tissue graft demonstrated superior mean root coverage compared to the first.
- Patient factors such as sex, age, smoking history, and time between surgeries did not significantly impact the obtained root coverage.

