Related Experiment Video
Updated: Jul 12, 2026

Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules
Published on: December 16, 2021
Neurocutaneous melanosis in a newborn with giant congenital melanocytic nevus
A D'Argenio1, P David, C Engohan
1Department of Neuroradiology, Erasmus Hospital ULB, Brussels, Belgium, and Department of Clinical Physiopathology, Radiodiagnostic Section, University of Florence, Florence, Italy.
Abstract:
Neurocutaneous melanosis (NCM) is known as a rare phakomatose characterised by large or numerous pigmented congenital nevi associated with leptomeninges melanin-containing deposits. We report a case of a newborn presenting at birth with a giant nevus covering about 40% of the total body surface. MRI showed T1 hyperintensities in the right amygdala and predominantly in the cerebellum corresponding to melanocytic cells.
