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Related Experiment Video

Updated: Jul 12, 2026

Protein Engineering by Yeast Surface Display
05:49

Protein Engineering by Yeast Surface Display

Published on: November 29, 2024

Protein engineering with bacterial display.

Patrick S Daugherty1

  • 1Department of Chemical Engineering, Biomolecular Science and Engineering, and Institute for Collaborative Biotechnologies, University of California, Santa Barbara, CA 93106, USA. psd@engineering.ucsb.edu

Current Opinion in Structural Biology
|August 31, 2007
PubMed
Summary

Bacterial surface display systems are advancing peptide and protein engineering. New tools allow for large-scale screening of protein libraries, enhancing engineering capabilities.

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Area of Science:

  • Biotechnology
  • Molecular Biology
  • Protein Engineering

Background:

  • Bacterial surface display systems have undergone significant advancements.
  • Efficient selection and screening strategies are crucial for protein engineering.

Purpose of the Study:

  • To highlight the advancements in bacterial display systems for peptide and protein engineering.
  • To emphasize the new capabilities offered by these systems in protein engineering.

Main Methods:

  • Utilizing bacterial surface display systems.
  • Employing efficient selection and screening strategies.
  • Leveraging cell-sorting instrumentation for large-scale library analysis.

Main Results:

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Last Updated: Jul 12, 2026

Protein Engineering by Yeast Surface Display
05:49

Protein Engineering by Yeast Surface Display

Published on: November 29, 2024

Bacterial Peptide Display for the Selection of Novel Biotinylating Enzymes
10:43

Bacterial Peptide Display for the Selection of Novel Biotinylating Enzymes

Published on: October 3, 2019

Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases
06:30

Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases

Published on: August 27, 2021

  • Bacterial display systems are becoming leading tools in peptide and protein engineering.
  • Large protein libraries can be analyzed and screened effectively.
  • Ease of bacterial manipulation offers new protein engineering capabilities.

    • Conclusions:

    • Advancements in bacterial display systems are revolutionizing protein engineering.
    • The integration of cell-sorting and bacterial manipulation expands the protein engineering toolbox.