Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Displaying inter-main chain hydrogen bond patterns in proteins.

K Belhadj-Mostefa1, R Poet, E J Milner-White

  • 1Department of Computing Science, University of Glasgow, UK.

Journal of Molecular Graphics
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of the Welch Allyn 'Vital Signs' blood pressure measurement device in pregnancy and pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology·2003
Same author

The N-terminal domain of MDM2 resembles calmodulin and its relatives.

Journal of molecular biology·1999
Same author

Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.

The Journal of pathology·1999
Same author

A natural grouping of motifs with an aspartate or asparagine residue forming two hydrogen bonds to residues ahead in sequence: their occurrence at alpha-helical N termini and in other situations.

Journal of molecular biology·1999
Same author

A recurring two-hydrogen-bond motif incorporating a serine or threonine residue is found both at alpha-helical N termini and in other situations.

Journal of molecular biology·1999
Same author

The partial charge of the nitrogen atom in peptide bonds.

Protein science : a publication of the Protein Society·1998
Same journal

HOLE: a program for the analysis of the pore dimensions of ion channel structural models.

Journal of molecular graphics·1996
Same journal

Analytically defined surfaces to analyze molecular interaction properties.

Journal of molecular graphics·1996
Same journal

Prediction of high-frequency electron paramagnetic resonance spectra of spin S = 3/2, 5/2 systems.

Journal of molecular graphics·1996
Same journal

Affecting the activity of soybean lipoxygenase-1.

Journal of molecular graphics·1996
Same journal

Why spin = 1, 2 species have no electron paramagnetic resonance signal under normal conditions: possible detection by electron paramagnetic resonance at frequency close to D value?

Journal of molecular graphics·1996
Same journal

Knowledge-based modeling of a legume lectin and docking of the carbohydrate ligand: the Ulex europaeus lectin I and its interaction with fucose.

Journal of molecular graphics·1996
See all related articles

New computer graphics methods visualize protein hydrogen bonds, aiding analysis of protein structures and domains. These techniques offer enhanced visualization beyond traditional protein depictions.

Area of Science:

  • Biochemistry
  • Structural Biology
  • Computational Biology

Background:

  • Protein structure analysis relies on visualizing interactions like hydrogen bonds.
  • Conventional protein visualizations often simplify complex structural features.

Purpose of the Study:

  • To introduce novel computer graphics techniques for displaying protein hydrogen bonds.
  • To enhance the visualization of protein structural motifs and domains.

Main Methods:

  • Development of a manipulable 3D model representing hydrogen bonds with smoothed alpha-carbon plots.
  • Creation of a 1D sequence-based display for viewing hydrogen bonds in relation to the amino acid sequence.
  • Illustration of techniques using two thiol proteases.

Related Experiment Videos

Main Results:

  • The developed methods facilitate easy examination of hydrogen bond patterns, including loop motifs, alpha-helices, and beta-sheets.
  • These visualizations provide more comprehensive information compared to conventional simplified protein images.
  • The techniques are implementable on UNIX-based computer graphics workstations.

Conclusions:

  • The proposed computer graphics techniques offer superior visualization of protein structures.
  • These methods can be broadly applied to display entire proteins and domains, revealing intricate details.
  • Enhanced visualization aids in a deeper understanding of protein architecture and function.