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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

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Related Experiment Video

Updated: Jul 12, 2026

Remote Magnetic Navigation for Accurate, Real-time Catheter Positioning and Ablation in Cardiac Electrophysiology Procedures
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Remote Magnetic Navigation for Accurate, Real-time Catheter Positioning and Ablation in Cardiac Electrophysiology Procedures

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Computer-assisted navigation applied to fetal cardiac intervention.

Stephen P Emery1, Jacqueline Kreutzer, Frederick R Sherman

  • 1Department of Obstetrics and Gynecology, Magee-Women's Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS
|August 31, 2007
PubMed
Summary

Computer-assisted navigation (CANav) significantly reduces procedure time for fetal aortic valve interventions. This technology improves needle delivery accuracy to the fetal heart, potentially aiding treatments for congenital heart conditions.

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Area of Science:

  • Medical Devices
  • Fetal Surgery
  • Cardiovascular Interventions

Background:

  • Prenatal cardiac interventions (PCI) for fetal aortic valve stenosis aim to prevent left ventricular hypoplasia.
  • Current 'freehand' needle delivery for PCI is technically challenging and time-consuming, limiting its application.

Purpose of the Study:

  • To develop and evaluate a computer-assisted navigation (CANav) system for precise fetal cardiac intervention needle placement.
  • To assess the impact of CANav on procedure time and accuracy in delivering a needle to the fetal heart.

Main Methods:

  • Developed a CANav system integrating 2D ultrasound and electromagnetic needle tracking.
  • Validated the system in vitro (water bath phantom), in vivo (adult rats), and in a pregnant sheep model.

Main Results:

  • CANav accurately tracked needle position in phantom and rat models.
  • In fetal sheep, CANav reduced needle delivery time to the left ventricle (2.9 min vs. 5.5 min, p < 0.05).
  • Time to cross the aortic valve was not significantly different between groups.

Conclusions:

  • CANav system effectively reduces the time for accurate needle delivery in fetal cardiac interventions.
  • This technology shows promise for improving PCI and other ultrasound-guided procedures for congenital heart defects.