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Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
Phosphate glass cement bone graft
1State University of New York, College of Ceramic Engineering, Alfred 14802.
Abstract:
The objective of this study was to prepare cement-forming substances from phosphate glasses for use as a bone graft. The glass-forming system of CaO-SrO-Na2O-P2O5 was explored and ten phosphate glasses were prepared of varying compositions. Cements were made by reducing the glass to powders and reacting them with a water solution of calcium hydroxide or phosphoric acid. The cements were evaluated by X-ray diffraction, electron microscopy, density and porosity measurements, pH change during reaction and solubility in water. Because of the water solubilities of these cement materials, they may be useful as bone grafts containing drugs such as antibiotics which would be slowly released as the graft material degrades.
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