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Related Experiment Videos

Ketorolac in acute headache management.

R N Harden1, T D Carter, C S Gilman

  • 1Dept. of Neurology, Medical University of South Carolina, Charleston 29425.

Headache
|July 1, 1991
PubMed
Summary

Ketorolac tromethamine effectively treated emergency department patients experiencing severe headache crises. This open-label trial showed significant pain reduction, warranting further controlled studies on its use for headache management.

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Area of Science:

  • Emergency Medicine
  • Pharmacology
  • Pain Management

Background:

  • Headache crisis presents a significant challenge in emergency departments.
  • Effective and rapid pain relief is crucial for patients with severe headaches.

Purpose of the Study:

  • To evaluate the efficacy of Ketorolac tromethamine in treating patients with headache crisis.
  • To assess pain reduction using the McGill Pain Questionnaire.

Main Methods:

  • An open-label trial involving twelve patients presenting with headache crisis.
  • Intramuscular administration of Ketorolac tromethamine at a dosage of 60 mg.

Main Results:

  • All twelve patients showed sufficient improvement, requiring no further emergent treatment.

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  • Statistically significant pain reduction was observed across all segments of the short form McGill Pain Questionnaire.

    • Conclusions:

    • Ketorolac tromethamine appears to be a potentially useful agent for managing headache crisis.
    • Further controlled studies are recommended to confirm these findings and establish its role in headache treatment.