Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mycobacterium malmoense: an easily missed pathogen.

S E Hoffner1, B Henriques, B Petrini

  • 1National Bacteriological Laboratory, Stockholm, Sweden.

Journal of Clinical Microbiology
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of HIV and <i>Mtb</i> infection among household contacts in East and Southern Africa.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026
Same author

Seagrass biochemical response to transplantation into contaminated sediments: A mesocosm experiment.

Environmental research·2025
Same author

Friction of Laser-Textured Zirconia Coated with a Platelet-Rich Fibrin.

Journal of dental research·2025
Same author

The effect of Zostera noltei recolonization on the sediment mercury vertical profiles of a recovering coastal lagoon.

Chemosphere·2023
Same author

Zostera noltei response to transplantation into historically Hg-contaminated sediments (A mesocosm experiment): Growth, bioaccumulation and photosynthetic performance.

Chemosphere·2023
Same author

Laser-assisted production of HAp-coated zirconia structured surfaces for biomedical applications.

Journal of the mechanical behavior of biomedical materials·2020

The BACTEC system offers a more sensitive and rapid method for detecting Mycobacterium malmoense in pediatric lymph node samples compared to traditional Löwenstein-Jensen egg medium cultures. This makes it a valuable complementary tool for diagnosing atypical mycobacterial infections.

Area of Science:

  • Medical Microbiology
  • Clinical Diagnostics
  • Pediatric Infectious Diseases

Background:

  • Lymphadenitis in children can be caused by atypical mycobacteria, including Mycobacterium malmoense.
  • Accurate and timely diagnosis is crucial for effective treatment of mycobacterial infections.
  • Traditional culture methods on Löwenstein-Jensen egg medium can be slow and less sensitive for certain pathogens.

Purpose of the Study:

  • To compare the diagnostic performance of the BACTEC system versus Löwenstein-Jensen egg medium for Mycobacterium malmoense detection.
  • To evaluate the sensitivity and speed of the BACTEC system in identifying M. malmoense in pediatric lymph node samples.
  • To determine the utility of the BACTEC system as a primary isolation method for atypical mycobacteria.

Main Methods:

Related Experiment Videos

  • Lymph node samples from children with lymphadenitis were analyzed.
  • Samples were cultured using both the BACTEC system and Löwenstein-Jensen egg medium.
  • Detection of Mycobacterium malmoense was the primary outcome measure.

Main Results:

  • The BACTEC system demonstrated significantly higher sensitivity in detecting Mycobacterium malmoense.
  • The BACTEC system provided a more rapid identification of M. malmoense compared to conventional culture.
  • Mycobacterium malmoense was identified as a causative agent in pediatric lymphadenitis.

Conclusions:

  • The BACTEC system is a superior method for the rapid and sensitive detection of Mycobacterium malmoense.
  • The BACTEC system is recommended as an adjunct to solid media for primary isolation of atypical mycobacteria like M. malmoense.
  • Improved diagnostic capabilities can enhance the management of pediatric mycobacterial lymphadenitis.