Ulcerative lesions of the palate associated with removable partial denture castings

Regions of inflammation with or without ulceration beneath removable partial dentures have been of concern to prosthodontists for many years. The etiology of these lesions has not been established, but potential factors are microbial infection, obstructive sialadenitis, and allergic-type reactions to the metal framework. A new etiological factor that may be involved is described. Focal pitting corrosion and by-products of corrosion in nickel-chromium alloys are discussed as toxic agents responsible for palatal lesions. Six patient reports that include results of tissue biopsy and EDAX analysis of casting are presented.