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Bickerstaff's brainstem encephalitis associated with typhoid fever.

G M Wali1

  • 1Department of Neurology, K.L.E. Society's Hospital, Belgaum, Karnataka State, India.

Postgraduate Medical Journal
|November 1, 1991
PubMed
Summary

Bacteriologically confirmed typhoid fever can lead to Bickerstaff

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Typhoid fever, a systemic infection caused by Salmonella Typhi, is known to have various neurological complications.
  • Bickerstaff's brainstem encephalitis (BBE) is a rare neurological disorder characterized by acute onset of ophthalmoplegia, ataxia, and altered consciousness.

Observation:

  • A 14-year-old boy presented with symptoms consistent with Bickerstaff's brainstem encephalitis.
  • The patient had a confirmed diagnosis of typhoid fever preceding the neurological syndrome.

Findings:

  • The case details the clinical presentation and neurological investigation results of a patient with co-occurring typhoid fever and BBE.
  • This presentation represents a rare neurological manifestation of typhoid fever.

Implications:

  • This case highlights the potential for Bickerstaff's brainstem encephalitis as a neuropsychiatric complication of typhoid fever.
  • Further research into the pathophysiology linking Salmonella Typhi infection and BBE is warranted.
  • Clinicians should consider BBE in the differential diagnosis of neurological syndromes in patients with typhoid fever.

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