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Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Variance01:15

Variance

The deviations show how spread out the data are about the mean. A positive deviation occurs when the data value exceeds the mean, whereas a negative deviation occurs when the data value is less than the mean. If the deviations are added, the sum is always zero. So one cannot simply add the deviations to get the data spread. By squaring the deviations, the numbers are made positive; thus, their sum will also be positive.The standard deviation measures the spread in the same units as the data.

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Concerning the theory of photoconductivity in infrared-sensitive semiconducting films.

Science (New York, N.Y.)·1950
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Related Experiment Video

Updated: Jul 10, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

Erratum.

E S Rittner

    Science (New York, N.Y.)
    |July 21, 1950
    PubMed
    Summary

    This paper corrects errors in a 1950 study on photoconductivity in infrared-sensitive films. The corrections clarify the theory of photoconductivity and semiconductor behavior.

    Area of Science:

    • Solid State Physics
    • Semiconductor Science
    • Optoelectronics

    Background:

    • The original study concerned the theory of photoconductivity in infrared-sensitive semiconducting films.
    • Published in Science (1950, 111), page 685.

    Purpose of the Study:

    • To provide critical corrections to the original publication.
    • To ensure accurate representation of the scientific findings regarding photoconductivity.

    Main Methods:

    • Textual analysis and correction of specific references and terminology.
    • Identification of erroneous figures and descriptive words within the original text.

    Main Results:

    • Correction of figure references from (10) or (5) to (1) or (2) on page 685.

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    Last Updated: Jul 10, 2026

    Molecular Evolution of the Tre Recombinase
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  • Deletion of the terms "fixed," "positive," and "electrons" from page 687.

    • Conclusions:

    • The corrected text provides a more accurate theoretical framework for photoconductivity.
    • Ensures precise understanding of infrared-sensitive semiconducting film behavior.