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Related Experiment Videos

Obstacles to implementing cancer clinical trials.

M A Johansen1, D K Mayer, H C Hoover

  • 1Medical/Oncology Intensive Care Unit, University Hospital, Boston, MA.

Seminars in Oncology Nursing
|November 11, 1991
PubMed
Summary

Conducting clinical trials faces significant hurdles, including patient recruitment challenges and high costs. Overcoming patient, physician, and nurse-related barriers is crucial for successful clinical research implementation.

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Area of Science:

  • Clinical research
  • Medical studies
  • Healthcare innovation

Background:

  • Clinical trials are essential for medical advancement but face implementation challenges.
  • Patient accrual and trial costs are significant obstacles for researchers.
  • Barriers exist at patient, physician, and nurse levels, hindering trial progress.

Purpose of the Study:

  • To identify and summarize key obstacles in clinical trial implementation.
  • To highlight the multifaceted nature of challenges in clinical research.
  • To provide insights into factors affecting patient accrual and trial costs.

Main Methods:

  • Literature review of clinical trial challenges.
  • Analysis of reported barriers in research publications.

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  • Synthesis of patient-related, physician-related, and nurse-related impediments.

    • Main Results:

    • Patient accrual difficulties represent a major challenge.
    • The high cost of clinical trials poses a significant problem.
    • Patient, physician, and nurse-related factors collectively impede trial execution.

    Conclusions:

    • Addressing patient accrual and cost issues is vital for clinical trial success.
    • Overcoming multifactorial barriers is necessary for efficient clinical trial implementation.
    • Understanding and mitigating patient, physician, and nurse-related obstacles can improve research outcomes.