Dynamic molecular structure and phase diagram of DPPC-cholesterol binary mixtures: a 2D-ELDOR study

Yun-Wei Chiang1, Antonio J Costa-Filho, Jack H Freed

  • 1Baker Laboratory of Chemistry and Chemical Biology, and National Biomedical ACERT Center for Advanced ESR Technology, Cornell University, Ithaca, New York 14853-1301, USA.

Summary

This study uses 2D electron-electron double resonance (2D-ELDOR) to map the phase diagram of DPPC-cholesterol model membranes. The technique reveals distinct liquid-ordered, liquid-disordered, and gel phases based on molecular dynamics.

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