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Related Experiment Videos

antiCODE: a natural sense-antisense transcripts database.

Yifei Yin1, Yi Zhao, Jie Wang

  • 1Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, CAMS & PUMC, Beijing 100730, China. yinyifei2005@yahoo.com

BMC Bioinformatics
|September 1, 2007
PubMed
Summary
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AntiCODE is a comprehensive database for natural antisense transcripts (NATs), integrating over 30,000 NAT pairs from 12 model organisms. This resource facilitates NAT research with advanced search and classification tools.

Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Natural antisense transcripts (NATs) are endogenous RNA molecules involved in gene regulation.
  • Large-scale NAT screens have generated substantial data, but a centralized repository was lacking.
  • AntiCODE was developed to consolidate and provide access to NAT data.

Purpose of the Study:

  • To create an integrated database for natural antisense transcripts (NATs).
  • To provide a comprehensive resource for researchers studying NATs.
  • To facilitate the analysis and understanding of NAT functions.

Main Methods:

  • Compilation of NAT data from 12 eukaryotic model organisms.
  • Development of an integrated database with browser, search, and BLAST functionalities.

Related Experiment Videos

  • Implementation of a classification system for NATs.

    • Main Results:

    • The antiCODE database contains over 30,000 non-redundant natural sense-antisense transcript pairs.
    • Includes efficient search parameters (species, accession number, overlap patterns, coding potential).
    • Offers a user-friendly platform for accessing and analyzing NAT information.

    Conclusions:

    • AntiCODE is the most comprehensive available database for NAT pairs.
    • The database serves as an integrated research platform for NAT studies.
    • Facilitates the study of NATs by providing organized and accessible data.