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Related Experiment Videos

Secondary optic nerve tumors.

N J Christmas1, M D Mead, E P Richardson

  • 1David G. Cogan Eye Pathology Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston.

Survey of Ophthalmology
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

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Secondary optic nerve tumors are more common than primary ones. They can spread from eye cancers, blood cancers, meningeal carcinomatosis, or distant tumors, rarely from orbital or late-stage brain tumors.

Area of Science:

  • Ophthalmology
  • Neurology
  • Oncology

Background:

  • Secondary optic nerve tumors are more prevalent than primary tumors.
  • Optic nerve involvement can stem from various oncological conditions.

Purpose of the Study:

  • To delineate the origins and pathways of secondary optic nerve tumors.
  • To differentiate secondary optic nerve tumors from primary and other orbital/cranial neoplasms.

Main Methods:

  • Literature review of secondary optic nerve tumor origins.
  • Analysis of tumor invasion pathways into the optic nerve.

Main Results:

  • Secondary tumors are more common than primary optic nerve tumors.
  • Common sources include intraocular, hematopoietic malignancies, meningeal carcinomatosis, and distant primary tumors.

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  • Orbital tumors infrequently invade the optic nerve; brain tumors involve it late.

    • Conclusions:

    • Understanding the diverse origins of secondary optic nerve tumors is crucial for diagnosis and management.
    • The pathways of spread highlight the interconnectedness of ocular, neurological, and systemic cancers.