Related Experiment Video
Updated: Jul 12, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
Published on: September 19, 2013
Molecular mechanisms exploited by Listeria monocytogenes during host cell invasion
Stéphanie Seveau1, Javier Pizarro-Cerda, Pascale Cossart
1Departments of Microbiology and Internal Medicine, Center for Microbial Interface Biology, Ohio State University, Columbus, OH 43210, USA. seveau.1@osu.edu
Abstract:
The facultative intracellular bacterial pathogen Listeria monocytogenes has evolved multiple strategies to invade a large panel of mammalian cells. Host cell invasion is critical for several stages of listeriosis pathology such as the initial crossing of the host intestinal barrier and the successive colonization of diverse target organs including the placenta. In this review, we address the main molecular mechanisms known to be used by L. monocytogenes during invasion of nonphagocytic cells and host tissues.
Related Concept Videos
Colonisation of Pathogens
Determinants of Bacterial Pathogenicity and Virulence
Intracellular Movement of Viruses and Bacteria
Cancer Cell Migration through Invadopodia
Adherens Junctions
Adherens Junctions are Dynamic
The endothelial cells...
Bacterial Meningitis

