Related Experiment Video
Updated: Jul 12, 2026

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H3 5,10,15-tris(pentafluorophenyl)corroles
Published on: March 18, 2015
trans-bis(3-aminoflavone-kappa2N,O)bis(perchlorato-kappaO)copper(II), a new potential antitumour agent
Agnieszka J Rybarczyk-Pirek1, Magdalena Małecka, Łukasz Glinka
1Department of Crystallography and Crystal Chemistry, University of Łódź, Pomorska 149/153, PL-90236 Łódź, Poland.
Abstract:
The title compound, trans-bis(3-amino-2-phenyl-4H-1-benzopyran-4-one-kappa(2)N,O(4))bis(perchlorato-kappaO)copper(II), [Cu(ClO4)2(C(15)H(11)NO(2))2], is composed of mononuclear units wherein the central Cu(II) cation occupies a crystallographic inversion centre. The cation is coordinated by two bidentate 3-aminoflavone ligands occupying the equatorial sites and by two perchlorate anions in the apical positions, thereby giving rise to a markedly elongated octahedral coordination geometry. Two symmetry-related intermolecular N-H...O hydrogen bonds link the molecules into chains of rings running parallel to the [100] direction, while intramolecular N-H...O hydrogen bonds help to determine the orientation of the apical perchlorate anions.
More Related Videos
Related Concept Videos
Antifungal Agents
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
![Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F68356.jpg&w=3840&q=50)
