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Skin substitutes and alternatives: a review

Jaimie T Shores1, Allen Gabriel, Subhas Gupta

  • 1Department of Plastic Surgery, Loma Linda University School of Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.

Advances in Skin & Wound Care
|September 1, 2007
PubMed
Summary

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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