Related Experiment Video
Updated: Jul 12, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Evidence-based infection control in the ICU (except catheters)
1Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany. gastmeier.petra@mh-hannover.de
New research highlights effective infection control in intensive care units (ICUs). Oral chlorhexidine rinse shows promise for reducing ventilator-associated pneumonia, a key finding for improving patient safety.
Area of Science:
- Critical Care Medicine
- Infectious Disease Prevention
- Hospital Epidemiology
Background:
- Intensive care units (ICUs) face significant challenges with nosocomial infections.
- Ventilator-associated pneumonia (VAP), urinary tract infections (UTIs), and surgical site infections (SSIs) are major concerns.
Purpose of the Study:
- To review recent randomized controlled trials and meta-analyses on infection control in ICUs.
- To focus on evidence for preventing VAP, UTIs, and SSIs.
Main Methods:
- Systematic evaluation of randomized controlled trials and meta-analyses published within the last year.
- Analysis of cohort studies with before-after designs.
Main Results:
- Evidence supports routine oral chlorhexidine gluconate rinse for decreasing VAP rates.
- Multimodal infection control programs demonstrated substantial reductions in infection rates.
- Findings endorsed existing recommendations and influenced current guidelines.
Conclusions:
- Significant interest exists in summarizing knowledge and updating guidelines for ICU infection control.
- Translating evidence-based infection prevention strategies into clinical practice is crucial.
- Future research should prioritize the implementation of infection prevention evidence in ICUs.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene
Hand washing...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Endocarditis IV: Nursing Management
