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Updated: Jul 12, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Magnetic resonance imaging of appendicular musculoskeletal infection
Radhesh K Lalam1, Victor N Cassar-Pullicino, Bernhard J Tins
1From the Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry Shropshire, United Kingdom.
Abstract:
Appendicular skeletal infection includes osseous and extraosseous infections. Skeletal infection needs early diagnosis and appropriate management to prevent long-term morbidity. Magnetic resonance imaging is the best imaging modality to diagnose skeletal infection early in most circumstances. This article describes the role of magnetic resonance imaging in relation to the other available imaging modalities in the diagnosis of skeletal infection. Special circumstances such as diabetic foot, postoperative infection, and chronic recurrent multifocal osteomyelitis are discussed separately.
Insights
Early diagnosis of appendicular skeletal infection is crucial. Magnetic resonance imaging (MRI) offers the best diagnostic approach for skeletal infections, guiding timely management and preventing long-term complications.
Area of Science:
- Orthopedics
- Radiology
- Infectious Diseases
Background:
- Appendicular skeletal infections encompass both bone (osseous) and surrounding tissue (extraosseous) infections.
- Prompt diagnosis and effective management are essential to mitigate long-term patient morbidity.
Purpose of the Study:
- To elucidate the role of Magnetic Resonance Imaging (MRI) in diagnosing skeletal infections.
- To compare MRI with other available imaging modalities for skeletal infection diagnosis.
Main Methods:
- Review of current literature on imaging modalities for skeletal infections.
- Emphasis on the diagnostic performance of MRI.
- Discussion of specific clinical scenarios including diabetic foot, postoperative infections, and chronic recurrent multifocal osteomyelitis.
Main Results:
- Magnetic resonance imaging (MRI) is identified as the optimal imaging modality for the early diagnosis of most skeletal infections.
- MRI provides superior visualization of osseous and extraosseous involvement compared to other modalities.
- Specific considerations for diabetic foot, postoperative, and chronic recurrent multifocal osteomyelitis are highlighted.
Conclusions:
- MRI is the leading imaging modality for diagnosing appendicular skeletal infections.
- Accurate diagnosis via MRI facilitates appropriate and timely management, reducing patient morbidity.
- Specialized approaches are necessary for complex cases like diabetic foot and chronic infections.
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