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Late vitamin K deficiency bleeding: 16 cases reviewed.
Hakan Doneray1, Huseyin Tan, Mustafa Buyukavci
1Department of Pediatrics, Ataturk University, Faculty of Medicine, Erzurum, Turkey. hdoneray@hotmail.com
Summary
Late vitamin K deficiency bleeding affects infants between 30-130 days old, often presenting with pallor and intracranial hemorrhage. Increased awareness of vitamin K prophylaxis is crucial for prevention.
Area of Science:
- Pediatrics
- Neonatology
- Hematology
Background:
- Late vitamin K deficiency bleeding (VKDB) is a serious condition in infants.
- Understanding its clinical and demographic features is essential for timely diagnosis and management.
Observation:
- This study analyzed 16 infants aged 30-130 days with late VKDB.
- Most infants had uneventful delivery and no family history of bleeding disorders.
- Parental awareness of vitamin K prophylaxis at birth was often lacking.
Findings:
- Pallor was the most common presenting symptom (62.5%).
- Intracranial hemorrhage occurred in 37.5% of cases, leading to death in 12.5%.
- No underlying illnesses explained the abnormal coagulation profiles.
Implications:
- Late VKDB remains a significant pediatric health concern.
- Healthcare providers and parents require education on the critical importance of vitamin K prophylaxis.
- Universal vitamin K administration at birth can prevent this potentially fatal condition.
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