Related Experiment Video
Updated: Jul 12, 2026
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
A true malignant schwannoma of the eighth cranial nerve: case report
L Fernando Gonzalez1, Gregory P Lekovic, Jennifer Eschbacher
1Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA.
Objective:
The clinical presentation, pathology, treatment, and outcome of a 43-year-old woman with a malignant peripheral nerve sheath tumor arising from a benign schwannoma of the eighth cranial nerve are presented.
Clinical Presentation:
Initially, the tumor was debulked. After finding malignant areas within the benign tumor, it was considered to be a malignant transformation of a previously benign tumor.
Intervention:
Aggressive total resection was obtained during a second-stage procedure. Postoperatively, the tumor bed was radiated for palliation.
Conclusion:
Despite surgery, radiation, and chemotherapy, the patient died rapidly as a result of disseminated metastatic disease.
