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Updated: Jan 20, 2026
Establishment of Central Cord Syndrome Model in C57BL/6J Mouse
Published on: September 8, 2023
Acute central cord syndrome arising from a cervical epidural abscess: case report
Robert Trombly1, James D Guest
1Department of Neurological Surgery, University of Miami, Miami, Florida 33136, USA.
Objective:
Acute central cord syndrome (ACCS) is a well-known sequela to spinal trauma but has rarely been associated with nontraumatic etiologies. Spinal epidural abscess (SEA) and spinal osteomyelitis/discitis are also well characterized clinical entities. Neither SEA nor osteomyelitis leading to ACCS has been previously reported.
Clinical Presentation:
In this report, a patient presented with refractory neck pain after minor trauma followed by development of left hand weakness and paresthesia, which progressed to a classic central cord injury clinical pattern over a period of 4 weeks.
Intervention:
Imaging and laboratory studies were consistent with SEA and osteomyelitis. Motor evoked potentials obtained during surgery definitively corroborated the clinical diagnosis of ACCS and supported a long tract pathophysiology.
Conclusion:
ACCS may be caused by SEA.
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