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Updated: Jul 12, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
[Imaging nodules within cirrhotic liver: how do I do it?].
1Service d'Imagerie Médicale, CHU Henri Mondor, Assistance Publique Hôpitaux de Paris, Faculté de Médecine Paris XII, 51 avenue du Maréchal de Lattre de Tassigny, 94010 Créteil Cedex, France. alain.luciani@hmn.aphp.fr
Cirrhosis involves liver damage and nodule formation, which can lead to cancer. Identifying these liver nodules is crucial for determining eligibility for liver transplantation in patients with hepatocellular carcinoma (HCC).
Area of Science:
- Hepatology
- Radiology
- Oncology
Background:
- Cirrhosis is a chronic liver disease marked by necrosis, fibrosis, and nodular regeneration.
- Regenerative nodules in cirrhosis can progress to dysplastic nodules and hepatocellular carcinoma (HCC).
- Liver transplantation offers improved survival for cirrhotic patients with HCC, contingent on eligibility.
Purpose of the Study:
- To review the imaging features of liver nodules in cirrhotic livers.
- To propose imaging strategies for evaluating liver nodules in patients considered for liver transplantation.
Main Methods:
- Literature review of imaging features of liver nodules in cirrhosis.
- Analysis of imaging strategies for HCC detection and evaluation in cirrhotic patients.
Main Results:
- Detailed description of imaging characteristics differentiating regenerative, dysplastic, and HCC nodules.
- Outline of a systematic imaging approach for nodule assessment in potential transplant candidates.
Conclusions:
- Accurate imaging interpretation of liver nodules is essential for managing cirrhosis and HCC.
- Defined imaging protocols aid in selecting cirrhotic patients with HCC for liver transplantation.
Related Concept Videos
Cirrhosis I: Introduction
Cirrhosis II: Pathophysiology
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
