Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Down-regulation and hibernating myocardium].

J D Schipke1

  • 1Institut für Experimentelle Chirurgie, Universität Düsseldorf.

Zeitschrift Fur Kardiologie
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Tonometry and pachymetry to evaluate fluctuations of intraocular pressure in the context of SCUBA diving].

Die Ophthalmologie·2023
Same author

Oxygen-enriched air reduces breathing gas consumption over air.

Current research in physiology·2022
Same author

Last Word on Viewpoint: Why predominantly neurological decompression sickness in breath-hold divers?

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Why predominantly neurological decompression sickness in breath-hold divers?

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Physical exercise might influence the risk of oxygen-induced acute neurotoxicity.

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc·2013
Same author

Perioperative and long-term development of anxiety and depression in CABG patients.

The Thoracic and cardiovascular surgeon·2013
Same journal

[Not Available].

Zeitschrift fur Kardiologie·2016
Same journal

[Not Available].

Zeitschrift fur Kardiologie·2016
Same journal

[On pathogenesis of coronary heart disease].

Zeitschrift fur Kardiologie·2016
Same journal

An overview of the evolution of the atherosclerotic plaque: from fatty streak to plaque rupture and thrombosis.

Zeitschrift fur Kardiologie·2016
Same journal

[Not Available].

Zeitschrift fur Kardiologie·2016
Same journal

[Reconstructive surgery of the aortic root].

Zeitschrift fur Kardiologie·2016
See all related articles

Hibernating myocardium, a state of reduced cardiac function due to decreased blood flow, is a protective mechanism. This viable, yet underperforming, heart tissue can recover function once blood flow is restored.

Area of Science:

  • Cardiology
  • Physiology

Context:

  • The term 'hibernating myocardium' describes a specific cardiac state, distinct from zoological hibernation.
  • This condition involves reduced myocardial mechanical function secondary to diminished coronary blood flow.
  • Evidence suggests this is an active, protective down-regulation to prevent ischemia-induced injury.

Purpose:

  • To elucidate the characteristics and protective nature of hibernating myocardium.
  • To differentiate hibernating myocardium from stunned myocardium and irreversibly damaged tissue.
  • To highlight the potential for functional recovery upon restoration of coronary blood flow.

Summary:

  • Hibernating myocardium is characterized by reduced function in hypoperfused areas that maintain active metabolism and viability.

Related Experiment Videos

  • Unlike stunned myocardium, which is dysfunctional during reperfusion, hibernating myocardium is a response to chronic hypoperfusion.
  • This state is considered a protective adaptation, allowing for rapid functional recovery after revascularization.

    • Impact:

    • Distinguishing hibernating myocardium is crucial for successful clinical interventions aimed at restoring coronary blood flow.
    • Understanding this mechanism can lead to improved therapeutic strategies for ischemic heart disease.
    • Identifies salvageable myocardial tissue, preventing misdiagnosis and enabling targeted treatments.