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Updated: Jul 12, 2026

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
Published on: May 5, 2018
[New diagnostic methods and modalities for congenital heart disease]
1Center for Cardiovascular Disease, Kurume University School of Medicine, Kurume, Japan.
Insights
Advancing 3D echocardiography aids congenital heart disease (CHD) diagnosis. Japan needs simpler prenatal screening programs and improved diagnostic tools to enhance patient outcomes for fetal CHD.
Area of Science:
- Cardiology
- Medical Imaging
- Prenatal Diagnosis
Background:
- Ultrasound technology for cardiovascular imaging has advanced significantly, including real-time 3D echocardiography and intracardiac echocardiography.
- 3D echocardiography plays a crucial role in assessing congenital heart diseases (CHD).
- Current prenatal screening for CHD in Japan is less efficient compared to some Western nations, leading to increased referrals and diagnoses.
Purpose of the Study:
- To highlight the need for improved prenatal screening programs for congenital heart diseases in Japan.
- To emphasize the growing number of fetal echocardiography referrals and CHD diagnoses.
- To advocate for the advancement and adoption of new diagnostic modalities for fetal CHD.
Main Methods:
- Review of current trends in fetal echocardiography referrals and CHD diagnoses in Japan.
- Assessment of the impact of 3D echocardiography on CHD evaluation.
- Analysis of the efficiency of existing prenatal screening systems for CHD.
Main Results:
- There has been a year-over-year increase in patient referrals for fetal echocardiography.
- The number of fetal CHD diagnoses has also risen annually.
- The gestational age at referral and diagnosis for CHD has notably increased in recent years.
Conclusions:
- Simpler prenatal primary screening programs for CHD are essential to improve patient prognosis.
- Further development and familiarization with advanced diagnostic modalities are required for better fetal CHD management.
Abstract:
Ultrasound imaging of cardiovascular structures has progressed rapidly from standard surface techniques to real-time 3-dimensional echocardiography and intracardiac echocardiography. Especially, 3-dimensional echocardiography is having a significant impact on the evaluation of congenital heart diseases (CHD). However, the present system of prenatal screening for CHD in Japan is not as efficient as it is in some Western countries. For this reason, the number of patient referrals for fetal echocardiography and the fetal diagnosis of CHD increased year after year. Gestational age at referral and at the diagnosis of CHD has increased rapidly in recent years. To improve the patient's prognosis, we should form more simple prenatal primary screening programs for CHD. In addition, we require the progression of the diagnostic modalities and familiarize these new diagnostic methods and modalities.
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