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Plasticity of neuroendocrine-immune interactions during aging
1Immunology Center, Research Dept. Inrca, Ancona, Italy.
Acta Neurologica
|October 1, 1991
Abstract:
Intact neuroendocrine-immune interactions are essential for the development and functional maintenance of both systems. Normal physiological aging appears to be, in part, dependent on age-related modifications of neuroendocrine-immune interactions. The thymus plays a major role in this context. Experimental manipulation at the thymic or neuroendocrine level may reciprocally correct the age-associated dysfunctions, suggesting the reversible nature of such phenomena.