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Orbital inflammatory disease.

Joseph R Lutt1, Lyndell L Lim, Pramit M Phal

  • 1Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA. luttj@ohsu.edu

Seminars in Arthritis and Rheumatism
|September 4, 2007
PubMed
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Orbital inflammatory disease (OID) presents with diverse symptoms and requires careful diagnosis. Rheumatologists play a key role in managing OID, often collaborating with ophthalmologists and internists.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Radiology

Background:

  • Orbital inflammatory disease (OID) encompasses various inflammatory conditions affecting orbital structures external to the eyeball.
  • Orbital involvement can be an early manifestation of systemic diseases like Graves' disease, Wegener's granulomatosis, and sarcoidosis.

Purpose of the Study:

  • To educate rheumatologists and internists on the clinical presentation, diagnosis, and management of orbital inflammatory disease (OID).
  • To highlight the importance of a multidisciplinary approach in managing OID.

Main Methods:

  • A comprehensive literature review was conducted focusing on orbital inflammatory disease.
  • The review synthesized information from rheumatology, ophthalmology, and radiology perspectives.

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Main Results:

  • Common causes of OID include idiopathic orbital inflammation, orbital myositis, and Tolosa-Hunt syndrome.
  • Management often involves systemic immunosuppression after excluding infectious and malignant etiologies.
  • Systemic diseases frequently present with orbital involvement.

Conclusions:

  • Rheumatologists must be adept at diagnosing orbital inflammatory disease.
  • Collaboration between rheumatology, ophthalmology, and internal medicine is crucial for effective OID management.