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Epidemiology of multiple sclerosis in western Herzegovina

Inge Klupka-Sarić1, Smiljana Ristić, Juraj Sepcić

  • 1Department of Neurology, School of Medicine, University of Mostar, Bosnia and Herzegovina.

Clinical Neurology and Neurosurgery
|September 4, 2007
PubMed
Abstract

Insights

Epidemiological studies reveal multiple sclerosis (MS) prevalence in western Herzegovina is moderate, with heterogeneous distribution. Primary progressive MS occurred exclusively in females, and initial visual symptoms were infrequent.

Area of Science:

  • Neurology
  • Epidemiology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease with varying geographical prevalence.
  • Understanding regional epidemiological data is crucial for public health planning and resource allocation.

Purpose of the Study:

  • To determine the epidemiological rates of multiple sclerosis (MS) in western Herzegovina.
  • To analyze the distribution and characteristics of MS patients in the region.

Main Methods:

  • A retrospective analysis of 81 multiple sclerosis patients (49 females, 32 males) was conducted.
  • Data were collected from medical records between 1994 and 2003 for the prevalence day of December 31, 2003.

Main Results:

  • The crude prevalence of MS was 27/100,000, with significant heterogeneity across municipalities.
  • Prevalence was highest in Posusje (56/100,000) and zero in Neum.
  • The annual incidence was 1.6/100,000, with a female-to-male ratio of 1.5. Primary progressive MS was observed only in females.

Conclusions:

  • Western Herzegovina represents an area of moderate risk for multiple sclerosis.
  • The study highlights a heterogeneous distribution of MS within the region.
  • Primary progressive MS exclusively affected females, and initial visual symptoms were uncommon.

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