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Updated: Jul 12, 2026

In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
Published on: November 10, 2011
The place of adsorption and biochromatography in extracorporeal liver support systems
C Legallais1, A Gautier, M Dufresne
1Technological University of Compiègne, UMR CNRS 6600 Biomechanics and Biomedical Engineering, BP 20529, 60205 Compiègne Cedex, France. cecile@legallais@utc.fr
Abstract:
Artificial and bioartificial liver devices aim at replacing some or all liver functions in the cases of end stage or fulminant disorders. Among all of its function, liver plays a key role in detoxification of substances that are hydrosoluble or bound to albumin. In this paper, the authors first reviewed the requirements for temporary liver support, then the adsorption-based systems that can be found on the market and finally propose new applications of biochromatography using perfusion-based bioartificial systems.
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