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Updated: Jul 12, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
Published on: April 7, 2023
[Hormone replacement Up-to-date. Selective estrogen receptor modulator (SERM) for the treatment of osteoporosis]
1National Center for Geriatrics and Gerontology, Department of Advanced Medicine, Japan.
Abstract:
Raloxifen is a selective estrogen receptor modulator (SERM) which is used for the treatment of osteoporosis. The major mechanism of action is the suppression of bone resorption. Evidences for the increase of bone mineral density and the decrease of vertebral fractures have been confirmed, while the effects on non-vertebral fractures may need more evidences. There is no doubt for that this drug is one of the major medicines for osteoporosis. On the other hand, extra-skeletal effects including those on cardiovascular systems should be studied further.
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