Related Experiment Video

Updated: Jul 12, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

Congenital heart disease in the 21st century

David Winlaw1

  • 1The Children's Hospital at Westmead, Sydney, NSW, Australia. davidw@chw.edu.au

Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine
|September 5, 2007
PubMed

Insights

Paediatric cardiac surgery for congenital heart disease (CHD) has advanced significantly. Adults with CHD now require specialized lifelong care, addressing emerging neurodevelopmental and long-term circulatory issues.

Area of Science:

  • Cardiology
  • Pediatric Surgery
  • Genetics

Background:

  • Paediatric cardiac surgery for congenital heart disease (CHD) has matured, offering good outcomes.
  • Advances in genetic studies and intensive care have improved management.
  • Contemporary strategies address low cardiac output syndrome.

Purpose of the Study:

  • To review the current status of paediatric cardiac surgery.
  • To highlight emerging issues like neurodevelopmental outcomes and Fontan circulation complications.
  • To describe a framework for adult CHD care, including common procedures and outcomes.

Main Methods:

  • Review of current paediatric cardiac surgery status.
  • Analysis of genetic studies and intensive care advancements.
  • Examination of neurodevelopmental status and Fontan circulation issues.
  • Framework development for adult CHD care.
  • Comparison of adult CHD care with routine adult cardiac intensive care.

Main Results:

  • Paediatric cardiac surgery yields good results for CHD.
  • Emerging concerns include neurodevelopmental status and Fontan circulation.
  • A framework for adult CHD care is proposed, detailing procedures and outcomes.
  • Adults with CHD require specialized follow-up in adult facilities.
  • Late complications are increasingly presenting in adult patients with complex CHD.

Conclusions:

  • Lifelong specialized care is essential for adults with CHD.
  • Transition from pediatric to adult care requires careful management and overlap in expertise.
  • Addressing neurodevelopmental and long-term circulatory issues is critical for improving quality of life.

More Related Videos

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System07:34

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System

Published on: May 5, 2018

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods08:28

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

Published on: March 10, 2020

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...