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[Premature birth and perinatal mortality 1982-1988. I]
S Bottino1, C De Micheli, N Roncaglia
1V Clinica Ostetrica e Ginecologica, Università degli Studi di Milano.
Insights
This study on premature deliveries found that higher gestational age (from 32 weeks) and birth weight (over 1500g) significantly reduce early neonatal mortality. Female infants also had lower mortality rates.
Area of Science:
- Perinatology
- Neonatology
- Obstetrics
Background:
- Premature delivery remains a significant concern in neonatal care.
- Understanding risk factors for preterm infant mortality is crucial for improving outcomes.
Purpose of the Study:
- To analyze trends in premature deliveries and associated early neonatal mortality.
- To identify factors influencing mortality rates in preterm infants.
Main Methods:
- Retrospective analysis of 1267 preterm births between 1982-1988.
- Data collected from the IV Clinica Ostetrica e Ginecologica, University of Milan.
- Comparison of mortality rates based on gestational age, birth weight, sex, and AGA status.
Main Results:
- The preterm birth rate averaged 9.8% (8.7-11.0%).
- Early neonatal mortality was 10.6% (8.3% excluding malformed newborns).
- Mortality significantly decreased for infants born at or after 32 weeks gestation and weighing over 1500g.
- Female infants had lower mortality (8.4%) than males (11.1%).
- Mortality was higher in Appropriate for Gestational Age (AGA) newborns (19.4%) compared to others (7.9%).
Conclusions:
- Gestational age and birth weight are critical determinants of survival in preterm infants.
- Sex and AGA status also play a role in early neonatal mortality.
- Further analysis of mortality causes is warranted.
Abstract:
The Authors analyzed the premature deliveries performed between 1982 and 1988 at the IV Clinica Ostetrica e Ginecologica of the University of Milan at the S. Gerardo Hospital, Monza, 1267 newborns out of 12507 were preterm. The rate was between 8.7 and 11.0% (average 9.8%). The early neonatal mortality is 10.6% (excluding malformed newborns, 8.3%), the late neonatal mortality is 12.7% (excluding malformed newborns, 9.8%). The early mortality is significantly lower starting from the 32nd week of pregnancy (35.4% vs 3.2%) and with a newborn's weight greater than 1500 grams (36.9 vs 3.2%). The early mortality is lower for females (8.4%) than for males (11.1%). In spite of other Authors, the early mortality is significantly higher than for AGA newborns (19.4 vs 7.9%). The causes of the early mortality are analyzed in detail.