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[Guideline for mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease
1Beijing Respiratory Disease Institute, Beijing Chaoyang Hospital, Capital University of Medical Science, Beijing, China.
Objective:
Chronic obstructive pulmonary disease (COPD) is one of the major causes of chronic morbidity and mortality throughout the world, while acute exacerbation of COPD (AECOPD) is one of the important causes for the patient to be hospitalized. As COPD is a disease state characterized by irreversible airflow limitation and dynamic pulmonary hyperinflation, the mechanical ventilation strategy for its AECOPD is different from other diseases. To improve the clinical result of mechanical ventilation for AECOPD, Chinese Society of Critical Care Medicine of Chinese Medical Association held a consensus conference to draft a guideline by categorizing all the information gathered from the literature into five grades from A to E, with A being the highest, according to a modified Delphi criteria. The main recommendations were as follows: 1. Noninvasive positive ventilation (NPPV) should be the routine option for AECOPD patients, particularly in hospitalized patients with mild to moderate exacerbations (7.25
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