[Screening for consecutive patient population with suspected CAD by 64-slice CT coronary angiography]

To evaluate the screening for consecutive patient population with suspected Coronary atherosclerotic heart disease (CAD) by noninvasive 64-slice computed tomographic coronary angiography.

2082 consecutive symptomatic subjects (1218 males, 868 female, with, mean age of 58.2 years old) with suspected CAD underwent MSCT studies. And 218 patients underwent coronary angiography within 7 days. Invasive coronary angiography was taken as golden standard for calculations of diagnostic accuracy.

Of 2082 subjects, 2063 (99.1%) were assessable, the mean examination duration was 4 minutes. Compared with CAG, the sensitivity of CTA to diagnose significant stenosis was 97.4%, specificity 90.1%, positive predictive value (PPV) 91.8% and negative predictive value (NPV) 96.8%.

Sixty-four-MSCT is accurate, convenient, noninvasive, safe means to coronary angiography with economic benefit. Thus, it can be considered as a valuable noninvasive screening technique.